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Ira Mellman
Ira Mellman, Ph.D. is an American cell biologist who discovered endosomes. He serves as Vice President of Research Oncology at Genentech in South San Francisco, California and is Professor of Biochemistry & Biophysics at the University of California, San Francisco. ==Research== Mellman's work has examined the role of endocytosis in cell metabolism and human disease. He was among the first to characterize the endosomal system. Later projects include investigation of LDL cholesterol receptor internalization, cellular sorting machinery, and the cellular basis for immunity. He is an authority on the cell biological mechanisms and function of dendritic cells, the cell type responsible for initiating the immune response, an interest that dates back to his postdoctoral period at Rockefeller University in the lab of Ralph Steinman, who won the Nobel Prize in 2011 for his discovery of dendritic cells.
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